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Guangzhou Huao Chemical Co.,Ltd
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Legal Lose Weight Hormones Orlistat Without Side Effect 96829-58-2

Legal Lose Weight Hormones Orlistat Without Side Effect 96829-58-2

Brand Name : Huao
Model Number : CAS: 96829-58-2
Certification : IOS 9001 ,USP ,GMP
Place of Origin : China
MOQ : 10g
Price : Skype:mia9403
Payment Terms : Western Union, MoneyGram, T/T,Bitcoin
Supply Ability : 25kg/month
Delivery Time : 3~5 work days
Packaging Details : Well disguised package
Product name : Orlistat
CAS : 96829-58-2
Appearance : Off-White Solid
Catagory : Pharmaceutical raw powder
Purity : 98%min.
Usage : Weight loss
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Pharmaceutical raw powder Orlistat For Weight Loss Without Side Effect


Quick detail :

Orlistat

  • Product name :Orlistat
  • CAS: 96829-58-2
  • MF: C29H53NO5
  • MW: 495.73
  • Categories: Pharmaceutical Raw Materials;Miscellaneous
  • Appearance : Off-White Solid
  • Usage : An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.


Dosage :

Orlistat works by blocking chemicals (enzymes) in your gut which digest fat. Nearly a third of the fat that you eat is blocked by orlistat. The undigested fat is not absorbed into your body, and is passed out with your stools (faeces). The normal dose is one capsule - 120 mg, three times a day with each meal. However, you do not need to take one if there is no fat in the meal or if you miss a meal.


Description of Orlistat :

Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity. It is marketed as a prescription drug under the trade name by Roche in most countries, and is sold over-the-counter as by GlaxoSmithKline in the United Kingdom and the United States.Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.

The effectiveness of orlistat in promoting weight loss is definite, though modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2-3 kilograms (4.4-6.6 lb) more than those not taking the drug over the course of a year.Orlistat also modestly reduces blood pressure, and appears to prevent the onset of type 2 diabetes, whether due to weight loss itself or to other effects; in a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.


Usage of Orlistat :

Orlistat is used for the treatment of obesity. The amount of weight loss achieved with orlistat varies. In one-year clinical trials, between 35.5% and 54.8% of subjects achieved a 5% or greater decrease in body mass, although not all of this mass was necessarily fat. Between 16.4% and 24.8% achieved at least a 10% decrease in body fat. After orlistat was stopped, a significant number of subjects regained weight-up to 35% of the weight they had lost.

The incidence of type 2 diabetes in an obese population over four years is decreased with orlistat (6.2%) compared to placebo (9.0%).Long-term use of orlistat also leads to a modest reduction in blood pressure (mean reductions of 2.5 and 1.9 mmHg in systolic and diastolic blood pressure respectively).


Test resluts of Orlistat :

ItemsSpecification Items
Appearancewhite or almost white crystalline powder,smell less
Melting Point42.0~46.0°C
Specific Rotation-31°~-39°(CHCl3,C=1)
IdentificationThe result of HPLC is consisitent to the reference one. The result of IR is consisitent to the reference one.
Related Substances≤ 0.5%
Total impurity≤ 1.0%
Single impurity≤ 0.1%
n-Hexane≤ 290ppm
Isopropyl ether≤ 5000ppm
Residual on Ignition≤0.1%
Sulphate≤ 0.05%
Heavy Metal≤ 20ppm
Purity≤ 99.0% ~ 99.9%


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